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The meaningful benefits shown by Jardiance in the Phase III EMPA-KIDNEY trial are welcome news for adults living with CKD in [the U.S.], Katherine Tuttle, executive director for research at Providence Inland Northwest Health, regional principal investigator for the Institute of Translational Health Sciences, professor of medicine at the University of Washington, and a steering committee member for the trial, said in a prepared statement

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A meta-analysis of randomized, controlled trials demonstrated an approximately 2-fold increase in hospitalizations for heart failure among non-selective and COX-2 selective-treated patients compared to placebo (5)