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Description

When lysosomes were disrupted by LLOME treatment, SCF FBXO27 was rapidly recruited to the broken lysosomes and ubiquitinated LAMP-2 to activate lysophagy 85

Kang, J

We explained that this important result arises from the very slow change of GSH as LIMITATIONS Our models are based on the underlying physiology and the kinetics of the enzymes, but no model can encompass the entirety of biological complexity