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SKU: 22481089529
Price: 20.85 USD
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Rating: 4.5985000000000005 (21 reviews)

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G.RovinaN.AkinosoglouK.AntoniadouA.AntonakosN.et al (2020)

Liver zonation - revisiting old questions with new technologies

Menon S, Dibble CC, Talbott G, Hoxhaj G, Valvezan AJ, Takahashi H

To investigate the consequences of individual SBBYSS mutations on KAT6B transcript abundance and histone acetylation, we used CRISPR/Cas9 genome editing and homology-directed repair to generate clonal HEK293T cell lines carrying specific SBBYSS mutations spanning the KAT6B gene, validated by sequencing (Figure 1A and Supplemental Tables 1 and 2