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Of note, this study confirmed findings from other studies whereby wounding led to the activation of Ca 2+ , ERK, and H 2 O 2 -mediated signalling cascades independently of each other 140

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In the study by iauskait and his team, highly metastatic human colon carcinoma cells were treated with sulforaphane, a bioactive compound found in cruciferous vegetables, in combination with the FOLFOX regimen (a combination of 5-FU, leucovorin, and oxaliplatin) to demonstrate an additive anticancer effect