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High-performance LC-MS/MS was used to perform high-sensitivity, wide-coverage, and high-throughput HM700-targeted quantification of 700 metabolites in these samples ( In detail, appropriate amounts of experimental or quality control (QC) samples were resuspended in 140 L of a 50% water/methanol solution, lysed, and centrifuged, and the supernatant was transferred to a new tube

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Notably, HGF is implicated in guiding spinal motoneurons to their target muscles in the limbs (Ebens et al., 1996)

The enhanced carbohydrate metabolic pathways in CUMS compared with control rats potentially suggest that a higher energy demand exists in depressed rats if such pathways are not just simply associated with microbial subpopulations less susceptible to host response(s) triggered by stressors