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These changes contribute to immune cell bioenergetic failure, T cell exhaustion, and cytosolic release of mtDNA, which can activate cGAS-STING and NLRP3 pathways to sustain chronic inflammation

These findings reveal a paradoxical gap between generally good diabetes knowledge and glycemic outcomes, suggesting that structural and contextual barriers, rather than knowledge deficits, may explain the persistent disconnect between theory and practice in low-income populations

Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and highly active antiretroviral therapy

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