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This because it is necessary a time-specific intervention for inducing beneficial and not detrimental effects, due to the different functions of specific microglia (McGeer and McGeer, 2015

Methods: iPSC-derived HLO cells were embedded in hydrogel on 16-well Qureator Curio-Barrier microfluidic devices and cultured in a standard incubator

Environmental exposures can similarly target the same processes affected by Parkinsons disease-associated gene variants, creating a system in which dopaminergic neurons are the victim of internal and external factors causing neurotoxicity

They are not FDA-approved for any medical purpose