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First, given that the aim of cMRTPs is to replace cigarettes, studies should always compare the effects of a cMRTP with those caused by cigarettes and, whenever possible, use smoking cessation as the benchmark as outlined previously [6]

Figure 13 shows a graph illustrating the filtering effect of an embodiment of the invention relative to conventional smoking articles, normalised to nicotine

Conversely, in less affluent countries, economic concerns and survival priorities may suppress the expression of these values (Figure 11A (left panel) partially supports this, as countries in Cluster 2 and 4 tend to have lower GDP per capita than those in Cluster 3

The Effects of Higher Cigarette Prices on Tar and Nicotine Consumption in a Cohort of Adult Smokers. Health Economics 13