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Abbreviations BDNF: Brain-derived neutrophic factor CAD: Coronary artery disease CEA: Carcinoembryonic antigen CO: Carbon monoxide DNA: Deoxyribonucleic acid ENDS: Electronic nicotine delivery systems EPA: Environmental Protection Agency FDA: Food and Drug Administration FEF: Forced expiratory flow FeNO: Fractional exhaled nitric oxide FEV: Forced expiratory volume FMD: Flow-mediated dilation FVC: Forced vital capacity GSH: Glutathione HR: Heart rate IHD: Ischemic heart disease IL: Interleukin MI: Myocardial infarction mRNA: Messenger RNA NO: Nitric oxide PAHs: Polycyclic aromatic hydrocarbons RNA: Ribonucleic acid ROS: Reactive oxygen species TNF: Tumor necrosis factor TXB 2 : Thromboxane B 2 VEGF: Vascular endothelium growth factor References Bou Fakhreddine HM, Kanj AN, Kanj NA

Smokeless Tobacco Market, By Geography North America Europe Asia Pacific Latin America Middle East and Africa The global smokeless tobacco market is a diverse and evolving landscape, characterized by significant regional variations in product preference, cultural acceptance, and regulatory environments

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