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BlochJBachoud-LviACDglonNLefaucheurJPWinkelLPalfiSet alNeuroprotective gene therapy for huntingtons disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study

While microglial proliferation has been observed in M1-mediated CRPS models, increases in phosphorylated ERK1/2 (Tyr204)/ERK1/2 failed to reach statistical significance in some studies (122)

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The proven efficacy of these compounds in scavenging ROS and their ability to conjugate with various therapeutic ligands theoretically enable them to target key NANT processes such as neuroinflammation and oxidative stress [73]