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"This causes a blotchy distribution of a lack of pigmentation in the skin." There are other reasons that someone would develop vitiligo, but about half the people who have the disorder get it before they turn 20

CONTRAINDICATIONS: It is recommended to avoid its use during pregnancy and breastfeeding, especially if not indicated by a doctor

Another study reported that crocin administration (10, 30, or 50 mg/kg) for 28 days during the juvenile period in a prenatal VPA-induced autism model in rats, alleviated the autism-like behaviors in the male offspring

One study demonstrated that calcitriol can influence the differentiation of T cell subsets by inhibiting the proliferation of immature CD4 + T cells into Th1 cells and promoting Th2 cell maturation, thereby affecting the balance between osteoblasts and osteoclasts (114)