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At clinical doses under supervision, the most common side effects are mild nausea in the first week (typically resolves by day 7 to 10), injection site reactions (redness, minor swelling, localized soreness lasting 24 hours), and occasional transient fatigue or mild headache in the first few days

Occupational exposures such as repetitive bending, heavy lifting, prolonged static postures, or exposure to vibration are known as risk factors for developing CLBP [27]

Patients often describe the sensation as a slight pinch or sting during injection-based treatments, while laser procedures might feel like a rubber band snapping against the skin

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