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However, there are indications that the astrocytic-neuronal-astrocytic interactions in formation, transfer and re-oxidation of transmitter glutamate and GABA may repeatedely require additional MAS function

Rake et al., 2010)

Therefore, we chose the sRUPP rat model, a well-established animal model of PE that directly mimics insufficient placental perfusion, a primary characteristic of PE 26,27