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Indeed, the residues of the L1 hairpin involved in the L1FnIII-2 interaction in IGF1R, such as K164 and Y173, are not conserved in IR

[DOI] [PubMed] [Google Scholar] 22.Malcovati L, Della Porta MG, Cazzola M

Therefore, clarifying the reference range of safe and effective doses will ensure the reproducibility of the antifibrotic therapeutic outcomes of AS-IV

While initially investigated in oncology, the strategy for reinstating wild-type p53 function may also prove beneficial in RA synovial fibroblasts, which possess analogous p53 missense mutations and exhibit modified phenotypes