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These compounds include pyruvate, which can be converted into acetyl-CoA and enter the tricarboxylic acid (TCA) cycle or be used for fatty acid synthesis, and -ketoglutarate, a precursor of glutamate and an intermediate of the TCA cycle

Selectively targeting TGF- with Trabedersen/OT-101 in treatment of evolving and mild ADRS in COVID-19

Bottom right : The resulting clinical manifestations include unexplained increases in end-tidal CO, masseter muscle spasm or generalized muscle rigidity, tachycardia, and rapidly rising core body temperature, which together characterize the malignant hyperthermia crisis

Probable role of beta2-adrenergic receptor gene haplotype in high-altitude pulmonary oedema