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Recent advances in the understanding of the roles gut peptides play in energy homeostasis has led to the identification of several that are known to modulate eating behaviour, including glucagon-like-peptide-1, oxyntomodulin, pancreatic polypeptide and peptide YY 336 , all of which respond to nutrients within the gut, interacting with specific receptors to regulate appetite

Therefore, there is an incremental cost of $790,567 in the first year of converting patients to oral vitamin B12

Frequently reported signs and symptoms of B 12 deficiency 9 23 26 27 28 29

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