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In addition to human studies, cell and murine studies should be conducted using more relevant models of exposure such as airliquid interface (ALI) cultures of primary cells and non-aqueous apical delivery of antioxidants and pollutants

Furthermore, 83% of participants hold a university degree, 69% never smoked, and only 4 participants occasionally smoked, the rest all quit smoking, one-third did not drink any alcohol, and two-thirds reported either 12 or 34 drinks per week, 66% reported taking supplements, almost half of the participants exercise 34 times a week with 88% moderate to lightly intensity and only 2 participants reported to be sedentary (Table 1 and Data Source File 1)

Finally, we reported the total number of unique aligned ORFans for each species (Supplementary Table 8)

After recovery, you might cautiously retry at lower concentration or frequency