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doi: 10.1172/JCI23865 240 RiusJGumaMSchachtrupCAkassoglouKZinkernagelASNizetVet al

They reduce inflammation: Inflammation is a major cause of thinning

Interestingly, the observations extracted from computational analysis were in accordance with the calculated in vitro enzyme inhibition activities, i.e., stronger interaction of C3G (glycosylation of 3-OH group) via A-ring with binuclear copper ion results in its complete oxidation by the enzyme against EC and CH compounds