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However, there are still significant challenges in targeting TME therapies

Therefore, we used DMF to induce HL60 cells to differentiate into neutrophils (CD11b+/CD66b+).After 5 consecutive days of DMF stimulation, HL60 cells were analyzed by flow cytometry

22 Hepcidin is encoded by the HAMP gene, and is upregulated by a lot of influence factors, such as bone morphogenetic protein (BMP), hemojuvelin (HJV) as well as human hemochromatosis protein (HFE), which regulating both the TFR and the BMP receptor on hepatocytes

In this study, GSH inhibited ferroptosis by activating the SLC7A11/GPX4 axis and reducing LPO levels to ultimately alleviate graft injury and promote survival