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These cells, which accumulate with age or stress, contribute to organ dysfunction by promoting chronic inflammation and impairing tissue repair

For individuals following plant-based diets, fortified foods (such as breakfast cereals, plant-based milk alternatives, and yeast extracts) or supplements become essential sources

In 3-KO mice, these reductions were absent, reinforcing the idea that 3-AR plays a necessary role in regulating the response of brown adipose tissue to these agents [2]