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Description

10.1021/tx060234h 129 McGillM

While the majority of patients respond favorably to topical corticosteroids (135), calcineurin inhibitors (136), and immunosuppressants (137), these treatments are often associated with significant adverse effects during long-term use (138)

MSC shows its immunosuppressive effect by directly or indirectly induces the polarization of CD4 + T cells to Tregs, and inhibits the proliferation of B cells and the production of antibodies