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Another mechanism that has been described as responsible for cisplatin cytotoxicity is the induction of reactive oxygen species (ROS), compounds that interact with macromolecular components, such as lipids, proteins and DNA, generating lesions 5

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Within the exposome framework, diet occupies a unique position: it simultaneously serves as a source of essential nutrients, bioactive compounds with chemopreventive potential, and chemical contaminants with carcinogenic properties (4, 5)