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Rheumatology 62 , 905913 (2023)

BRET measurements were carried out in HEK293T cells co-expressing Nluc-fused mas-GsBP1, mas-GsBP2, mas-KB1753 (in D, E and F), mas-GRK RH (in G), or mas-PRG RH (in H), with either wild-type (WT) or constitutively active (QL) mutants of Gi3 (in D), Go (in E), Gz (in F), Gq (in G), or G13 (in H) fused to a YFP, as indicated

SEM micrographs were taken at various magnifications at 25 kV and 5 kV for porcine cornea and BPCDX samples, respectively

Secondly, toxicity of PQ 2+ can be explained by production of superoxide that has numerous targets in the cell, among them iron-containing enzymes