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These findings not only advance our understanding of metabolic adaptation in cancer progression but also highlight the therapeutic potential of targeting LDHB lactylation or the SLC7A11-GSH axis to suppress metastasis and sensitize tumors to ferroptosis-inducing therapies

This confirmed the relevance of the CENPT-GCLC-GSH signaling axis in the ferroptosis pathway

Likewise, action potentials and associated contractions can propagate only into regions of musculature where the inhibitory motor neurons are inactivated

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