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I., Cuzic S., Brajsa K., Mildner B., Bokulic A., Situm K., et al

The cells do not need constant stimulation, they need periodic reactivation

But those studies, McGuire says, dont have a lot of evidence behind them, and if you look on Reddit or other places where people are talking about it, he says, it appears that most people are recommending repeated doses

Animal studies have documented significant improvements in Morris water maze performance, radial arm maze accuracy, and novel object recognition tasks, with effects persisting for extended periods after treatment suggesting lasting changes in neural connectivity rather than temporary pharmacological stimulation