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Disruption of the regional homeostasis of ERMCS affects their remodeling ability, leading to impaired intercellular communication and even the occurrence of ALS

doi: 10.1016/j.brainresrev.2006.08.005

The latter is still the gold standard technique for assessing the epithelial barrier function, whereas in vivo techniques, including putative blood biomarkers such as intestinal fatty acid-binding protein and zonulin, are broadly used despite limitations