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Figure 1 ncRNAs can actively regulate energetic signaling by targeting key metabolic transporters and enzymes, or by directly or indirectly controlling the expression of tumor suppressors or oncogenes (Iorio and Croce, 2012)

A more detailed overview of ncRNAs implicated in inflammation is discussed in (O'connell et al., 2012)

Small molecule inhibitors targeting ASCT2 and other glutamine transporters have been shown to inhibit glutamine uptake and consumption and exhibit antitumor effects in various cancer models

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