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Abstract Chronic kidney disease-mineral and bone disorder (CKD-MBD) is recognized as a systemic syndrome that manifests with a range of complications including mineral dysregulation, skeletal abnormalities, and vascular calcification (VC)

It was found that beyond all these listed roles, insulin also modifies neuronal activity, and improves memory function in the brain

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Aureli M, Samarani M, Loberto N, Bassi R, Murdica V, Prioni S, Prinetti A, Sonnino S (2014) The glycosphingolipid hydrolases in the central nervous system