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At the cellular level, we saw that the mitochondria of the muscle, also known as the energy factories of the cell, function less well and that they produce less energy," said study co-author Rob Wst, an assistant professor of human movement sciences at Vrije University, in Amsterdam

Besides SARS-CoV-2, we included influenza A and dengue as two highly human pathogenic prototypic RNA viruses to identify promising broad-spectrum antiviral targets

A recent clinical study further confirmed that NSW disrupts 24-hour rhythms of PER2, PER3, BMAL1, and ESR2 in PBMCs, impairs the inverse correlation between PER2 and BMAL1, and alters PER1 and ESR1 expression patterns, highlighting a misalignment in the peripheral circadian network associated with NSW schedules 212

Sies H (1993) Ebselen, a selenoorganic compound as glutathione peroxidase mimic