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In the new study, the MIT and Dana-Farber team wanted to extend that search into tissue samples from patients with pancreatic cancer, using immunopeptidomics a strategy that involves extracting the peptides presented on a cell surface and then identifying the peptides using mass spectrometry

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While gastrointestinal symptoms (nausea, vomiting, diarrhea, constipation, and abdominal pain) are the most frequently reported side effects, fatigue and asthenia (weakness) are recognized drug-associated effects