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448,449 IMpassion130 also showed that atezolizumab plus nab-paclitaxel administered as first-line treatment produced significantly longer PFS in both the intention-to-treat population and the subgroup of patients with PD-L1-positive tumors

Blank cuvettes contained no GSH and showed an initial fluorescence reading of 1.5-2.2 units which did not significantly change with time

Molecular dynamic investigations proposed that, in the process of ferroptosis, alterations in lipid composition cause changes in cellular membrane shape and curvature, leading to exposure to more oxidants, irreversible destruction to the membrane integrity, and ferroptotic cell death (Jaganjac et al., 2020)