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In contrast, shoot-based mechanisms primarily involve intracellular Fe compartmentalisation and enzymatic detoxification through superoxide dismutase (SOD) and ascorbate peroxidase (APX) 24,25,96

Moreover, the absence of intestinal PPAR blocks the ability of PPAR agonist GW501516 to elevate HDL-cholesterol levels

In an ideal world, preclinical and clinical studies would always use the same techniques (e.g., the same anticoagulant for sample collection, process samples from one individual at a time, control for environmental confounds, etc.)