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Merkeley, H

This study also postulates that H 2 O 2 could diffuse into the cytoplasm where it will either be neutralized by the antioxidant pathway or convert into hydroxyl radicals and cause free radical damage to the cell

27 HernandezI.AlegreL.BoschS

Therefore, ferroptosis inducers include compounds that inhibit system Xc - (erastin, imidazole ketone erastin (IKE), sulfasalazine) 7,9 , compounds that directly inhibit GPX4 (RSL3, ML-210) 8 , and compounds that inhibit glutathione synthesis (buthionine sulfoximine) 8