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Anesthesia was administered prior to drug injections to ensure animal comfort and minimize stress

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Collectively, these findings suggest that modulating key factors within the HIF-1 signaling pathway, both upstream and downstream, can effectively optimize effector cell metabolism, diminish the proliferation and overactivation of abnormal, self-reactive cells, and subsequently ameliorate tissue inflammation in SLE patients, particularly those with LN

Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1