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Actually, there is a long history regarding the clinical application of HDACi for epilepsy [129, 130]

Research indicates that the UPR induced by ERS exerts dual regulatory effects in both tumor cells and immune cellssustaining tumor cell survival while also reshaping the immune microenvironment through non-cell-autonomous mechanisms

10.1007/s00210-019-01664-9 [DOI] [PubMed] [Google Scholar] Shati A

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