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Individuals with a history of pulmonary, neurologic, hepatic, rheumatic, hematologic, or renal chronic disease, who were treated with immunosuppressive therapy in the 6 months prior to screening, or who used medication or supplements that may have confounded the study results were also excluded

10.1194/jlr.M027433 25 MatsumotoJ.OgawaH.MaeyamaR.OkudairaK.ShinkaT.KuharaT.et al (1997)

Studies have shown that clock gene expression is dysregulated in kidney tissues under pathological conditions, contributing to disease progression

Byrne R, Todd I, Tighe PJ, Fairclough LC (2019) Autoantibodies in chronic obstructive pulmonary disease: a systematic review