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Nature immunology

Important caveat: Side effect data comes primarily from animal studies

Although ubiquitin is remarkably stable, earlier measurements and our analysis found that the energy of UT3 ridge and cleft binding to two ubiquitin molecules is enough to compensate for ubiquitin unfolding energy

A notable single nucleotide polymorphism (SNP) in the TM6SF2 gene is rs58542926, in which guanine (G) is replaced by adenine (A) at position 499 of the coding region (c