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After full recovery, correct cannulation was tested by observing water drinking responsiveness after infusion of 1 l human angiotensin II (Sigma-Aldrich, A9525) at a concentration of 24 M in artificial cerebrospinal fluid (distilled water with 125 mM NaCl, 2.5 mM KCl, 2.6 mM NaHCO 3 , 1.25 mM NaH 2 PO 4 2H 2 O, 25 mM d-glucose monohydrate, 1 mM MgCl 2 , 2 mM CaCl 2 )

Chingle RM, Imai M, Altman S, Saito D,Takahashi N,Burke TR

Langerhans and dendritic cells to initiate an autoimmune response

Cholesterol can not only induce ectopic fatty acids accumulation, reshape an immunosuppressive microenvironment, activate hepatic stellate cells, and influence membrane fluidity or protein function, to further promote tumorigenesis in HCC but also activate NK cell proliferation or recruitment, and promote CD44 translocation into lipid rafts, so that prohibit HCC (Zhou and Sun, 2021)