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These WRKY genes regulate both biotic and abiotic stress responses [220]

3.4 Inducible modeling systems Knock-in GEMMs for BRAF V600E -mutated gliomas are alternative models that involve conditional and inducible systems such as the Cre-loxP system to allow the expression of BRAF V600E under the control of the endogenous promoter and enhancer sequences in a cell-specific or time-specific manner upon the activation of Cre recombinase (121), which can be induced by delivering either tamoxifen or Cre-expressing viruses such as adeno-associated viruses and adenoviruses (111)

Gene 552 , 195198 (2014)

Effects of weight change on plasma leptin concentrations and energy expenditure