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J Blood Med 9:141144 Mandal PK, Kartthik S (2019) Autoimmune hemolytic anemia: an uncommon cause of elevated fetal hemoglobin

Systemic diseases like Sjgren's syndrome, diabetes, and HIV/AIDS affect saliva production

Interestingly, at acidic pH, the protein uses NAD phosphate (NADP) as a substrate to produce nicotinamide adenine dinucleotide phosphate (NAADP), which is hydrolyzed to ADP-ribose 2'-phosphate (ADPRP) [2]