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Some research shows that in people living with HIV, combining treatment for smoking cessation, anxiety and depression is more effective than treatment for smoking cessation alone

Participants who reported not smoking SPECTRUMs, not wanting to continue in the study, or who were lost to follow-up from V1 to V3 did not remain eligible to participate and were withdrawn from the study

Given the prevalence of vaping, and the co-occurrence of mental health challenges and polysubstance use with vaping, it is critical to understand perceptions and motivations for vaping within individuals with OUD and the impact of vaping on opioid use, health conditions and treatment outcomes in this high risk population