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16 , e1009260 (2020)

SLC25A32 transports THF into mitochondria to support one-carbon (1 C) metabolism that converts serine into formate, which is then exported into the cytosol for de novo purine biosynthesis (Fig

Follow-up visits track appetite, weight trend, body composition, and tolerance, and the dose or combination is adjusted from there rather than left on autopilot