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When administered to the treatment group of rats, GA demonstrated a dose-dependent reduction in fibrotic area, inflammatory infiltration, fat degeneration, as well as levels of hyaluronic acid (HA), type IV collagen (cIV), ALT, AST, and gamma-glutamyl transferase (-GT)

if response is inadequate and the concentration is less than 200 ng/ml, the dose may be increased to approach 400 ng/ml

In pharmacokinetics studies its excretion was relatively high ranging from 60% to 72% suggesting that its content in the diet is mostly sufficient (Eissenstat et al., 1986