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292,293 A clinical trial in 20 women with fibromyalgia and without celiac disease or IBS found pain and symptom severity were reduced after six months on a gluten-free diet

Recent studies have shown that insulin-mediated suppression of hepatic gluconeogenesis occurs indirectly through the ability of insulin to suppress adipocyte lipolysis and the flux into liver pyruvate carboxylase, the rate-limiting enzyme in gluconeogenesis (183, 200)

AOD-9604 appears to activate the same lipolytic pathway through a mechanism distinct from the classical GH receptor, which is why it doesn't trigger those anabolic/hormonal downstream effects

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