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Given its role in the tryptophan-tryptophan-serotonin-melatonin pathway, the group also speculated that the abnormalities in nicotinic acid and its metabolites may be a contributor to the disordered sleep pattern observed in autistic patients

Panos, Aristotle University of Thessaloniki, Greece Reviewed by Amy Kathryn Stark, University of Michigan, United States Angel Ortega Valero, University of Valencia, Spain Updates Copyright 2026 Aqil, Yaldo, Alahdab, Hsiung, Tawfik and Al-Shabrawey