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When our defence mechanisms become overloaded, they can no longer combat oxidation effectively

The enzyme cytochrome P450, involved in the metabolism of xenobiotics and endogenous compounds, can leak electrons to oxygen during its catalytic cycle, producing superoxide radicals [60]

73 In another case report, a 64-year-old man presented with acute respiratory distress syndrome due to COVID-19 severe pneumonia and secondary bacterial lung infection was admitted to Taihe Hospital in Shiyan, China and was given repeated bedside bronchoscopy at intervals of 1 day or 2 days with a large dose of 10,00015,000 mg/time of N-acetylcysteine nebulized inhalation solution lavage combined with routine nebulization and sputum suction airway management

Jung HI, Kong MS, Lee BR, Kim TH, Chae MJ, Lee EJ, Jung GB, Lee CH, Sung JK, Kim YH (2019) Exogenous glutathione increases arsenic translocation into shoots and alleviates arsenic-induced oxidative stress by sustaining ascorbate-glutathione homeostasis in rice seedlings