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10.1016/j.brainres.2012.09.022 Brain Res

ROS can directly damage biological structures, including lipids, proteins, and DNA, contributing to cell death, necrosis, and apoptosis (Juan et al., 2021)

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Nevertheless, in addition to the properties of probes themselves (molecular weight, lipophilicity, amphiphilicity, ionic charge and protein/lipid binding characteristics) intracellular distribution can also depend on the phenotype of the target cells 117