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SKU: 19911757007
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Description

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

Arican et al

For extraction, 1 g of fungal mycelium was mixed with 10 mL of ethyl acetate (EtOAc) and incubated at room temperature on an orbital shaker (Santarius, Gttingen, Germany) at 100 rpm for 72 h

These agents are particularly useful as add-on therapies but may also suffer from incomplete CNS penetration and systemic side effects such as hypertension and insomnia due to their off-target activity