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doi: 10.3390/healthcare10030487 170 BarcelosIPHaasRH

Astragalus and Ganoderma lucidum polysaccharides attenuate TLR2/4myeloid differentiation primary response 88 (MyD88)NF-B activation in intestinal epithelial and myeloid cells, suppressing transcription of pro-inflammatory genes such as iNOS, COX-2, and TNF-, while enhancing IL-10 and transforming growth factor- (TGF-) expression via signal transducer and activator of transcription 3 (STAT3)-regulated anti-inflammatory signalling [185,274]

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