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Reintroduction of XKR8 reinstated PS exposure in XKR8 KO HL-60 cells during apoptosis and PMA-induced NET formation and successfully rescued NET formation (Fig

First-in-human biomarker-driven phase I trial of the potent and selective glutaminase-1 (GLS1) inhibitor IACS-6274 (IPN60090) in patients with molecularly selected advanced solid tumors

Perhaps the internal resistance were slightly high to begin with anyway, so double it

In another report, it was shown that K48-linked ubiquitinated cGAS is directly sequestered into the lysosome for degradation by interacting with the selective autophagy receptor p62 ( Figure 3 )